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Figure 2
Factor I cofactors. (a) The crystal structure of the fI cofactor rat CrrY1–4 (PDB entry 2xrb ) as a cartoon representation rainbow coloured from the N-terminus (red) to the C-terminus (blue). (b) Overlay of the crystal structures of CrrY1–4 (PDB entries 2xrb and 2xrd ; rainbow coloured) on the structure of fH1–4 from the C3b–fH1–4 binary complex (PDB entry 2wii ; Wu et al., 2009 ![]() ![]() ![]() |